Recent publications

Morris water maze, novel object recognition and social interaction

Chevere-Torres, I.; Maki, J.M.; Santini, E.; Klann, E. (2012). Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin. Neurobiology of Disease, 45 (1), 156-164.

Open field and elevated plus maze

Oliver, P.; Davies, K.E. (2009). Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk. HMG Advanced Access.

Open field, elevated plus maze and novel object recognition

Tereshchenko, Y.; Brandewiede, J.; Schachner, M.; Irintchev, A.; Morellini, F. (2008). Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice. Behavioural Brain Research, 191, 280-284.

Morris water maze

Nishimura, M.; Gu, X.; Swann, J.W. (2011). Seizures in early life suppress hippocampal dendrite growth while impairing spatial learning. Neurobiology of Disease, 44 (2), 205-214.
Zheng, Y.; Hamilton E.; Begum, S.; Smith, P.F.; Darlington, C.L. (2011). The effects of acoustic trauma that can cause tinnitus on spatial performance in rats. Neuroscience, 186, 48-56.
Oyagi, A.; Moriguchi, S.; Nitta, A.; Murata, K.; Oida, Y.; Tsuruma, K.; Shimazawa, M.; Fukunaga, K.; Hara, H. (2011). Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation. Brain Research, 1419, 97-104.
Sartori, C. R.; Vieira, A. S.; Ferrari, E.M.; Langone, F.; Tongiorgi, E.; Parada, C.A. (2011). The antidepressive effect of the physical exercise correlates with increased levels of mature BDNF, and proBDNF proteolytic cleavage-related, p11 and tPA. Neuroscience, 180, 9-18.
Chang, W. P.; Huang X. P.; Downs, D.; Cirrito, J.R.; Koelsch, G.; Holtzman, D.M.; Ghosh, A.K.; Tang, J. (2011). "beta-Secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice." Faseb Journal, 25 (2), 775-784.
Kim, M. E.; Park, H. R.; Gong, E.J.; Choi, S.Y.; Kim, H.S.; Lee, J. (2011). Exposure to bisphenol A appears to impair hippocampal neurogenesis and spatial learning and memory. Food and chemical toxicology, 49 (12), 3383-3389.
VanGuilder, H. D.; Farley, J. A.; Yan, H.; Kirk, van, C.A.; Mitschelen, M.; Sonntag, W.E.; Freeman, W.M. (2011). Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline. Neurobiology of Disease, 43 (1), 201-212.
Maeda, T.; Maeda, A.; Casadesus, G.; Palczewski, K.; Margaron, P. (2009). Evaluation of 9-cis-Retinyl Acetate Therapy in Rpe65-/- Mice. Investigative Ophthalmology & Visual Science, 50(9), 4368-4378.
Mitschelen, M.; Garteiser, P.; Carnes, B.A.; Farley, J.A.; Doblas, S.; Demoe, J.H.; Warrington, J.P.; Yan, H.; Nicolle, M.M.; Towner, R.; Sonntag, W.E. (2009). Basal and hypercapnia-altered cerebrovascular perfusion predict mild cognitive impariment in aging rodents. Neuroscience, 164(3), 918-928.
Taylor, G.A.; Rodriguiz, R.M.; Greene, R.I.; Daniell. X.; Henry, S.C.; Crooks, K.R.; Kotloski, R.; Tessarollo, L.; Philips, L.E.; Wetsel, W.C. (2008).Behavioral characterization of P311 knockout mice. Genes, Brain and Behavior, 7, 786-795.

Novel object recognition test

Haydar, S.N.; Ghiron, C.; Bettinetti, L.; Bothmann, H.; Comery, T.A.; Dunlop, J.; La Rosa, S.; Micco, I.; Pollastrini, M.; Quinn, J.; Roncarati, R.; Scali, C.; Valacchi, M.; Varrone, M.; Zanaletti, R. (2009). SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist. Bioorganic & Medicinal Chemistry, 17, 5247-5258.
Roncarati, R.; Scali, C.; Comery, T.A.; Grauer, S.M.; Aschmi, S.; Bothmann, H.; Jow. B.; Kowal, D.; Gianfriddo, M.; Kelley, C.; Zanelli, U.; Ghiron, C.; Haydar, S.; Dunlop, J.; Terstappen, G.C. (2009). Procognitive and neuroprotective activity of a novel α7 nocotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders. The Journal of Pharmacology and Experimental Therapeutics, 329, 459-468.
Simmons, D.A.; Rex, C.S.; Palmer, L.; Pandyarajan, V.; Fedulov, V.; Gall, C.M.; Lynch, G. (2009). Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proceedings of the National Academy of Sciences, 106, 4906-4911.
Sydserff, S.; Sutton, E.J.; Song, D.; Quirk, M.C.; Maciag, C.; Li, C.; Jonak, G.; Gurley, D.; Gordon, J.C.; Christian, E.P.; Doherty, J.J.; Hudzik, T.; Johnson, E.; Mrzljak, L.; Piser, T.; Smagin, G.N.; Wang, Y.; Widzowski, D.; Smith, J.S. (2009). Selective a7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. Biochemical Pharmacology, 78, 880-888.
Benice, T.J.; Raber, J. (2008). Object recognition analysis in mice using nose-point digital video tracking. Journal of Neuroscience Methods, 168, 422-430.

Open field activity

Devall, A.J.; Liu, Z. W.; Lovick, T.A. (2009). Hyperalgesia in the setting of anxiety: Sex differences and effects of the oestrous cycle in Wistar rats.Psychoneuroendocrinology, 34, 587-596.
Garcia-Garcia, A.L.; Elizalde, N.; Matrov, D.; Harro, J.; Wojcik, S.M.; Venzala, E.; Ramfrez, M.J.; Del Rio, J.; Tordera, R.M. (2009). Increased Vulnerability to Depressive-Like Behavior of Mice with Decreased Expression of VGLUT1. Society of Biological Psychiatry, 66, 275-282.
Kakefuda, KI.; Fujita, Y.; Oyagi, A.; Hyakkoku, K.; Kojima, T.; Umemura, K.; Tsuruma, K.; Shimazawa, M.; Ito, M.; Nozawa, Y.; Hara, H. (2009). Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection. Biochemical and Biophysical Research Communications, 387, 784-788.

Barnes maze

Hao, W.; Liu, Y.; Liu, S.; Walter, S.; Grimm, M.O.; Kiliaan, A.J.; Penke, B.; Hartmann, T.; Rübe, C.E.; Menger, M.d.; Fassbender, K. (2011). Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer’s disease-related symptoms and pathology. Brain, 134, 278-292.

Other applications

Battaglia, F.P.; Kalenschera, T.; Cabral, H.; Winkel, J.; Bosa, J.; Manuputy, R.; Lieshout, T. van; Pinkseb, F.; Beukers, H.; Pennartza, C. (2009). The Lantern: An ultra-light micro-drive for multi-tetrode recordings in mice and other small animals. Journal of Neuroscience Methods, 178, 291-300.
Fonio, E.; Benjamin, Y.; Golani, I. (2009). Freedom of movement and the stability of its unfolding in free exploration of mice. PNAS, 106(50), 21335-21340.
Mao, Y.; Ge, X.; Frank, C.L.; Madison, J.M.; Koehler, A.N.; Doud, M.K.; Tassa, C.; Berry, E.M.; Soda, T.; Singh, K.K.; Biechele, T.; Petryshen, T.L.; Moon, R.T.; Haggarty, S.J.; Tsai, L.H. (2009). Disrupted in Schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3B/B-Catenin signaling. Cell, 136, 1017-1031.
Pather, S.; Gerlai, R. (2009). Shuttle box learning in zebrafish (Danio rerio). Behavioural Brain Research, 196, 323-327.
Venerosi, A.; Cutuli, D.; Colonnello, V.; Cardona, D.; Ricceri, L.; Calamandrei, G. (2008). Neonatal exposure to chlorpyrifos affects maternal responses and maternal aggression of female mice in adulthood. Neurotoxicology and Teratology, 30, 468-474.