Social interaction test

The study of social interaction can be done in a variety of set-ups, all having one thing in common: the study of behaviors between two or more animals. Behaviors of interest could be sexual and mating behavior, agonistic behavior, maternal behavior, etc. Often differences between treatment groups or genetic strains are investigated. Most tests are straightforward and conducted in an open field or home cage environment.

For a complete set-up, combine EthoVision XT and the Social Interaction Module with PhenoTyper or an open field.

 

Examples of parameters
  • Percentage of time in which two animals are within each other’s proximity.
  • Proximity of individual body points, such as nose point and tail base, of two rodents.
  • Mean distance between two animals.
  • Speed at which one animal moves away or towards another animal.
  • Number of nose-nose contacts.
Components

Optional components

Typical components

Optional components

Selected publications
  • Lazar, N.; Rajakumar, N.; Cain, D. (2007). Injections of NGF into neonatal frontal cortex decrease social interaction as adults: a rat model of schizophrenia. Schizophrenia Bulletin, 34, 127-136.
  • Shultz, S.R.; MacFabe, D.F.; Ossenkopp, K-P.; Scratch, S.; Whelan, J.; Taylor, R.; Cain, D.P. (2008). Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: Implications for an animal model of autism. Neuropharmacology, 54, 901-911.