Budapest

Zebrafish in Budapest, and more!

Thursday, 22 June, 2017

Interested in zebrafish research?  Read three blog post about zebrafish behavior research or visit us at the 10th European Zebrafish Meeting in Budapest, Hungary this summer.

Zebrafish 2017

This meeting will cover a large range of topics on zebrafish and other teleost species, from aquaculture to tissue dynamics, from the study of early organogenesis to the application of fish in chemical biology. Noldus representatives Ruud Tegelenbosch and Marjolein Kops will be attending this conference.

zebrafish2017

Three blog posts about zebrafish behavior research

1)      Social buffering in zebrafish

Shared sorrow is half a sorrow, according to the old proverb. Faustino et al. recently found that zebrafish showed less fear in a threatening situation when they were not alone. So social support is not only important for us humans, but also for zebrafish!

Faustion et al. exposed fish to an alarm substance. Some fish were alone, while others were exposed to conspecific cues – meaning that they were swimming in shoal water, were in visual contact with their shoal in an adjacent tank, or both.

Curious to find out if fish behaved differently? Read the blog about social buffering in zebrafish to learn more!
 

2)      Isolated and stressed zebrafish as a model for major depression

Depression: a fifth (!) of us cope with it, making it the most prevalent psychiatric disorder. Prof. Gerlai recently investigated the interaction between mild stress and developmental isolation, two factors that can elicit depression-like behavior, in zebrafish models.

The reason that the lab of Prof. Robert Gerlai investigated both the Unpredictable Chronic Mild Stress and the social isolation paradigm, is because the interaction between the two is not clear. Read the blog post to learn how this affected behavioral and neurochemical changes in zebrafish.
 

3)      How optogenetics is used to study the stress response in zebrafish larvae

Stress might seem like a bad word, but it does have its perks. A recent study by Rodrigo J. De Marco uncovered the role of the pituitary in zebrafish larvae behavior after the onset of stress.

De Marco argues that zebrafish are excellent model subjects in this case: “This is what all this is about: exploiting a unique opportunity (larvae are small, transparent and have a fully functional stress axis) to - ‘non-invasively’- ask important questions. For example, can pituitary products exert fast effects on behavior?”
 

Read the full blog post to learn about the outcomes of this study and how De Marco used optogenetics in his research.