A. Dirks, L. Groenink, M. Verdouw, J. van der Gugten and B. Olivier (Utrecht, The Netherlands)
Exploration of the behavioral consequences of chronic CRH overproduction in mice of two established transgenic lines (CRH-OE2122 and CRH-OE2123) in behavioral paradigms reflecting different aspects of stress, anxiety and depression.
In this study, The Observer and EthoVision allowed easy recording and analysis of specific behaviors, resulting in an extensive description of the behavioral profile of the mutant mice overexpressing CRH.
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