Garret Stuber, University of North Carolina at Chapel Hill, UNC Neuroscience center, Chapel Hill, USA
Joshua Matulonis, Research Foundation at Stony Brook University, USA
Prescilla Perrichon, IFREMER – La Rochelle – France
Nick Birch, Scottish Crop Researcher Institute, Dundee, UK
Marina Pleskacheva, Moscow State University, Lab. Of Physiology, Genetics and Behavior, Moscow, Russian Federation
Samuel Adeosun, University of Mississippi Medical Center, Jackson, USA
Thomas van Groen, University of Alabama at Birmingham, Cell Biology department, Brimingham, USA
Jacqueline Womersley, University of CapeTown, Department of Human Biology, Cape Town, South Africa
David Eilam, Tel-Aviv University, Zoology Department, Israel
Allan V. Kalueff, Department of Pharmacology, Tulane University Medical School, USA
Diane Lim, University of Pennsylvania, USA
Matt Andrzejewski, University of Wisconsin-Madison, USA
Joshua Herrington, Florida International University, USA
Craig Kinsley, University of Richmond, USA
Roman Bucher, University of Koblenz-Landau, Germany
Prof. Cachot, University of Bordeaux, France
What’s new in EthoVision XT 10
EthoVision XT 10: coming soon! A peek at the new features:
Automatic Rat Behavior Recognition
Revolutionize the way you work with automatic recognition of rat behavior. This new system will make your research more efficient and objective. It is as accurate as a human observer and has a better repeatability, giving you consistent results every time. No extra training is needed when using a different experimental set-up or strain of rats. The system is also tireless, allowing you to perform ‘round the clock’ observations in an efficient manner.
Recognized behaviors include:
- rearing against the wall
- unsupported rearing
Batch acquisition and analysis
Save valuable time by letting EthoVision XT track all your video files in one go and run automatic analysis on all your data with one push of the button!
Group statistics and charts
View the results of groups in tables and in graphs to get an immediate feel for your data. Compare treatment groups alongside each other or look at the differences within treatment groups over time.
This unique built-in feature gives you an intuitive presentation of your data, and enables you, in one glance, to answer the question ‘In which part of the arena did the animal spend most of its time?’ You can select data and compare heatmaps of groups or individuals. Of course, you can export them for use in scientific publications and presentations.
Series of trials from live video feed
Acquire a series of trials automatically. Take a water maze test, for example. Set each trial to last for 60 seconds, or until the animal has reached the platform, and set an interval of 10 minutes in between trials to replace the animal.
EthoVision XT runs on Windows 7 and Windows 8, on 32 and 64 bit computers.
Other recent new features (EthoVision XT 9)
An animal can be sitting still, but that does not automatically mean that it is freezing. To solve this, EthoVision XT has a new method for activity detection. Now you can now detect body displacement and orientation of the animal, as well as activity levels within the arena. This combination is really powerful for detailed analysis of fear conditioning or operant tests.
The new activity detection is also very suitable to detect zebrafish embryonic tail flicks or convulsion behavior, or for the heartbeat monitoring of zebrafish larvae. The heartbeath detection (free software with EthoVIsion XT 9) extracts a power spectrum from your EthoVision XT data to identify the heartbeat.
Another great advantage of activity detection is that it even works in situations where detection is dificult due to poor lighting or light animals on a light background (or dark animals on a dark background).
Studies on new drugs are often discontinued due to negative side effects of those drugs on the heart. Cardiovascular defects and cardiotoxic effects of compounds can be easily measured in zebrafish larvae thanks to their transparency, small size, and ease of manipulation. With the EthoVision XT Heartbeat Detector this now becomes very easy and can be done without any fluorescent labeling technologies.
How? EthoVision XT comes with Activity Detection, a new method to measure the changes in pixels within an area between samples. When this area is the heart region of a zebrafish larva, the heart activity is detected.
This data is used by the Heartbeat Detector to calculate the dominant frequency and determine the heart rate of the zebrafish larva.
All you have to do is record the activity of the zebrafish larval heart area and the heart rate is calculated for you!
Your experiment, your choice in equipment
In addition to proven solutions with analog cameras, EthoVision XT supports a range of digital cameras, such as FireWire or GigE. These are particularly interesting in situations that require a high frame rate (quickly moving animals such as fish) or high resolution (small animals such as larvae in a large arena). Low-end digital cameras are useful if you want to create a cost-efficient solution for less demanding tests.
Picking your set-up usually involves more than just choosing a camera. Some experiments (operant tasks or conditioning) require interactions with hardware. That is why EthoVision XT has the Trial & Hardware Control Module; to control external equipment such as pellet feeders, lights, sound generators, and more, from within the software. By using EthoVision XT, you can even use behavioral based events in your operant task. This is taking operant conditioning to the next level!
Batch acquisition: analysis overnight
EthoVision XT allows you to acquire the tracking data of your animal live, but in some cases it is more practical to create video files of your experiments, and process these later. For example, when EthoVision XT is being used for other experiments. Processing these video files has become much easier, because you can now run a batch acquisition. Simply connect the video files to the according trials in your trial list. Now you can acquire your data overnight!