Rats have a complex repertoire of social behaviors. As social behavior is an accessible 'read-out system', it is often used for studying brain-behavior relationships. Although there have been studies on the consequences of social isolation on behavior and physiology in rats, the mechanisms underlying this apparent drive to keep social contact have not been elucidated. This article focuses on the behavioral and physiological characteristics of this phenomenon. Quantative measures were obtained with EthoVision.

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