Applications | |
Cerebellar ataxia model (Lurcher mutant) Data courtesy of Dr. Jaroslav Voller and Dr. Jan Cendelin, Department of Pathophysiology, Faculty of Medicine, Charles University in Prague, Czech Republic | |
Significant deficits in locomotor performance: increased stand duration (hind paws), increased swing duration, decreased stride length, decreased swing speed, decreased interlimb coordination, and increased diagonal support. | |
Stroke (middle cerebral artery occlusion) model (SD rats) Data courtesy of Dr. Jialing Liu and Dr. Yonggang Wang, Department of neurosurgery, UCSF and the behavioral core facility at the SFVAMC, San Francisco, USA. | |
Significant deficits in locomotor performance: decreased paw pressure, area contact and paw angle of forepaws, and increased ipsilateral support and relative print positions. | |
Spinal demyelination model (C57BL6 mouse) Data courtesy of Dr. David Lafont, RBM Merck Serono, Italy | |
Significant deficits in locomotor performance: decreased paw pressure and dutcy cycle of the left hind paw, and increased paw pressure and duty cycle of right front paw. Observed increase in the propulsion phase ("max contact at") of left front and right hind paws, and decrease in stride length of left hind paw. | |
Spinal cord injury (contusion) model (Sprague Dawley rats) Data courtesy of Dr. Candace Floyd Department of Physical Medicine & Rehabilitation, University of Alabama at Birmingham, USA | |
Significant deficits in locomotor performance: decreased interlimb coordination and duty cycle. | |

