Selected publications - Water maze

A selection of recent publications:

  • Adedayo, A.D.; Aderinola, A.; Adekilekun, T.A.; Olaolu, O.O.; Olanike, A.M.; Olayemi, I.K. (2018). Morphine-alcohol treatment impairs cognitive functions and increases neuro-inflammatory responses in the medial prefrontal cortex of juvenile male rats. Anatomy & Cell Biology, doi: 10.5115/acb.2018.51.1.41

  • Bálentová, S.; Hajtmanová, E.; Filová, B.; Borbélyová, V.; Lehotský, J.; Adamkov, M. (2018). Effects of fractionated whole-brain irradiation on cellular composition and cognitive function in the rat brain. International Journal of Radiation Biology, doi:10.1080/09553002.2018.1425805

  • Brombacher, T. M.; De Gouveia, K. S.; Cruywagen, L.; Makena, N.; Booley, F.; Tamgue, O.; Brombacher, F. (2018). Nippostrongylus brasiliensis infection leads to impaired reference memory and myeloid cell interference. Scientific Reports, 8, 2958.

  • Caccamo, A.; Belfiore, R.; Oddo, S. (2018). Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer’s disease. Neurobiology of Aging, doi: 10.1016/j.neurobiolaging.2018.03.032.

  • Cevika, O.S.; Sahina, L.; Tamerb, L. (2018). Long term treadmill exercise performed to chronic social isolated rats regulate anxiety behavior without improving learning. Life Sciences, 200, 126–133.

  • Chen, H.; Xiang, S.; Huang, L.; Lin, J.; Hu, S.; Mak, S.-H,; Wang, C.; Wang, Q.; Cui, W.; Han, Y. (2018). Tacrine(10)-hupyridone, a dual-binding acetylcholinesterase inhibitor, potently attenuates scopolamine-induced impairments of cognition in mice. Metabolic Brain Disease, doi:10.1007/s11011-018-0221-7.

  • Chen, X.; Wang, S.; Zhou, Y.; Han, Y.; Li, S.; Xu, Q.; Xu, L.; Zhu, Z.; Deng, Y.; Yu, L.; Song, L.; Chen, A.P.; Song, J.; Takahashi, E.; He, G.; He, L.; Li, W.; Chen, C.D. (2018).Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway. Nature Communications, doi: 10.1038/s41467-017-02531-y.

  • Fekete, C.; Vastagh, C.; Dénes, Á.; Hrabovszky, E.; Nyiri, G.; Kalló, I.; Liposits, Z.; Sárvári, M. (2018). Chronic amyloid β oligomer infusion evokes systained inflammation and microglial changes in the rat hippocampus via NLRP3. Neuroscience, doi: 10.1016/j.neuroscience.2018.02.046.

  • Fischer, K.D.; Houston, A.C.W.;  Desai, R.I.; Doyle, M.R.; Bergman, J.; Mian, M.; Mannix, R.; Sulzer, D.L.; Choi, S.J.; Mosharov, E.V.; Hodgson, N.W.; Bechtholt, A.; Miczek, K.A.; Rosenberg, P.A. (2018). Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine. Psychopharmacology, doi: 10.1007/s00213-018-4848-1.

  • Hou, Z.; Tian, R.; Han, F.; Hao, S.; Wu, W.; Mao, X.; Tao, X.; Lu, T.; Dong, J.; Zhen, Y.; Liu, B. (2018) Decompressive craniectomy protects against hippocampal edema and behavioral deficits at an early stage of a moderately controlled cortical impact brain injury model in adult male rats. Brain Research Bulletin, doi: 10.1016/j.bbr.2018.02.010.

  • Knezovic, A.; Osmanovic Barilar, J.; Babic, A.; Bagaric,R.; Farkas, V.; Riederer, P.; Salkovic-Petrisic, M. (2018). Glucagon-like peptide-1 mediates effects of oral galactose in streptozotocin-induced rat model of sporadic Alzheimer’s disease. Neuropharmacology, 135, 48-62. 

  • Majkutewicz, I.; Kurowska, E.; Podlacha, M.; Myslinska, D.; Grembecka, B.; Rucinski, J.; Pierzynowska, K.; Wrona, D. (2018). Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer’s disease. Brain Research, 1686, 19-33.

  • Marschner, L.; Schreurs, A.; Lechat, B.; Mogensen, J.; Roebroek, A.; Ahmed, T.; Balschun, D. (2018). Single mild traumatic brain injury results in transiently impaired spatial long-term memory and altered search strategies. Brain Research Bulletin, doi: 10.1016/j.bbr.2018.02.040. 

  • McPherson, C.A.; Zhang, G.; Gilliam, R.; Brar, S.S.; Wilson, R.; Brix, A.; Picut, C.; Harry, G.J. (2018). An Evaluation of Neurotoxicity Following Fluoride Exposure from Gestational Through Adult Ages in Long-Evans Hooded Rats. Neurotoxicity Research, doi: 10.1007/s12640-018-9870-x

  • Montgomery, K.S.; Bancroft, E.A.; Fincher, A.S.; Migut, E.A.; Provasek, V.; Murchison, D.; DuBois, D.W. (2018). Effects of ethanol and varenicline on female Sprague-Dawley rats in a third trimester model of fetal alcohol syndrome. Alcohol, doi: 10.1016/j.alcohol.2018.02.006.

  • Orr, A.G.; Lo, I.; Schumacher, H.; Ho, K.; Gill, M.; Guo, W.; Kim, D.H.; Knox, A.; Saito, T.; Saido, T.C.; Simms. J.; Toddes, C.; Wang, X.; Yu, G.-Q.; Mucke, L. (2018). Istradefylline reduces memory deficits in aging mice with amyloid pathology. Neurobiology of Disease, 110, 29-36.

  • Pilipenko, V.; Narbute, K.; Beitnere, U.; Rumaks, J.; Pupure, J.; Jansone, B.; Klusa, V. (2018). Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocininduced Alzheimer's disease. European Journal of Pharmacology, 818, 382-399. 

  • Titus, D.J.; Wilson, N.M.; Alcazar, O.; Calixte, D.A.; Dietrich, W.D.; Gurney, M.E.; Atkins, C.M. A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury. Neurobiology of Learning and Memory, 148, 38-49.

  • Wang, B.; Han, S. (2018). Inhibition of Inducible Nitric Oxide Synthase Attenuates Deficits in Synaptic Plasticity and Brain Functions Following Traumatic Brain Injury. The Cerebellum, doi: 10.1007/s12311-018-0934-5.

  • Yu, Y.; Zhao, Y.; Teng, F.; Li, J.; Guan, Y.; Xu, J.; LV, X.; Guan, F.; Zhang, M.; Chen, L. (2018). Berberine improves cognitive deficiency and muscular dysfunction via activation of the AMPK/SIRT1/PGC-1A pathway in skeletal muscle from naturally aging rats. The Journal of Nutrition, Health & Aging, doi:

  • Zhang,  A.-H.; Yu, J.-B.; Sun, H.; Kong, L.; Wang, X.-Q.; Zhang, Q.-Y.; Wang, X-J. (2018). Identifying quality-markers from Shengmai San protects against transgenic mouse model of Alzheimer's disease using chinmedomics approach. Phytomedicine, doi: 10.1016/j.phymed.2018.04.004.

  • Zheng, X.; Liang, L.; Hei, C.; Yang, W.; Zhang, T.; Wu, K.; Qin, Y.; Chang, Q. (2018). Bilateral olfactory mucosa damage induces the disappearance of olfactory glomerulus and reduces the expression of extrasynaptic α5GABAARs in the hippocampus in early postnatal Sprague Dawley rats. Neurotoxicity Research, doi: 10.1007/s12640-018-9893-3.

These and some other studies on AD as well as how video tracking was incorporated in their Morris water maze experiments have been described in a new FREE white paper.

Go back to the Morris water maze →