Testing in a

Barnes maze

The Barnes maze is a well-known paradigm to study spatial learning and memory. This maze consists of a circular table with circular holes around the circumference. The goal is for the animal to reach the box that is positioned beneath one of the holes with the aid of visual cues.

A food reward in the goal box can help the training process. In some experiments the surface of the table is brightly lit, serving as an aversive stimulus that motivates the mouse or rat to find (and hide in) the goal box.

Testing in a Barnes maze
 

Test spatial learning in rats and mice

Besides investigating the learning curve of the animal over consecutive trials, the searching strategy of the animal can also be of interest. While some animals randomly search for the correct hole, others might systematically check each hole in certain patterns. When animals move directly to the correct hole independent of their starting position, this indicates spatial memory has formed.

 
brown mouse on a white gloved hand
 


dorego takes cage wall css

Get started

EthoVision XT helps you get started quickly, whether you are a first time user or an experienced one. The built-in templates have arena definition and detection settings pre-set, which you can fine-tune as needed.

 
 


Customer quote

"EthoVision XT provides objective data and has strengthened my research output."

Dr. P. Amoateng|University of Ghana, Ghana

 


Areas of interest in the Barnes maze

Of course, within the Barnes maze, the different holes are of interest. These are predefined in the template, all you have to do is drag and drop these circles to the correct place in the video image within EthoVision XT. Specify which has the goal box underneath, and now EthoVision XT can combine this information with the tracking data you are about to acquire. The Barnes maze is available in different sizes and different options.

 
barnes maze
 


Tracking movement and behavior in detail

The EthoVision XT Multiple Body Points Module is able to detect and track not only the center point, but also the nose point and tail base of mice and rats. This allows for the accurate measurement of an animal’s relative position. In this case, it helps you discriminate nose-dipping, for example.

 


Relevant blogs

secret-social-role-ca2-hippocampus

Revealing the secret social role of the CA2 hippocampus

Aggressive behavior is adaptive for most species. But how is this aggressive behavior mediated in the brain? A recent study indicates that the hippocampus is a crucial neural component in mediating social recognition.
know-if-an-animal-nauseated

How to know if an animal is nauseated

Nausea is a prominent factor influencing the quality of life for patients undergoing chemotherapy. That is why it is useful to study the nauseating side effects of therapies or the anti-nauseating potential of drugs.
anabolic-steroids-rat-study

Exercise vs anabolic steroids: a rat study

A recent study shows that the use of anabolic steroids diminishes the positive effects of exercise in rats.
 
Ready to kick start your research?
Want better insights and faster results? Contact us now to learn how we can help you!

Full name

Email address

Country