We like zebrafish and the promise they hold for neuroscience research. That’s one of the reasons why Noldus is a sponsor of the 16th Australia and New Zealand Zebrafish meeting that will take place next week at Queensland’s Gold Coast. It’s also a good reason to mention some of the most interesting zebrafish studies we have been highlighting on our blog lately.
Netting stress and coping styles
Two weeks ago I mentioned the research of Christian Tudorache and his colleagues from Leiden University (The Netherlands). I had the pleasure of meeting him a while back at the Radboud University Nijmegen, where we both attended a Zebrafish MasterClass. Tudorache’s research on coping styles of zebrafish involves a netting stress procedure for larvae and showed significant differences in both behavior and physiology between pro-active and re-active coping styles, even at this early age. You can read the blog post here, and their study (published in Stress) here.
Inhibitory avoidance learning
The Radboud University that I mentioned above has a great zebrafish research facility of their own. One of the topics they have been working on is inhibitory avoidance learning in zebrafish. Remy Manuel, Marnix Gorissen, and Ruud van den Bos did us a great favor by writing up a guest blog listing different aspects that influence this type of learning in zebrafish. Older zebrafish, for example, require more training time. And keeping the animals under long periods of light (extending their ‘day’) also does not help. Curious what the effects of stress and enrichment are? Read the blog post here, or one of the publications listed underneath the post.
Regeneration in zebrafish
Zebrafish have a regenerative ability, and this just might hold the key to spinal cold injury treatment. While humans affected with this disability might be severely disabled for life, zebrafish can recover because they seem to be able to re-express the necessary genes to grow back the axons projecting from the brain. Liping Ma and colleagues have identified the enzyme legumain to be necessary for spinal cord recovery in zebrafish. Read about their research publication in PLoS ONE.
The zebrafish fan club
May last year I published a post on the paper of Prof. Allan Kalueff and his colleages which is still one of favorites. It lists a number of reasons why zebrafish have become so useful and popular in neuroscience research. You can read it here.
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