Recent work done by Khor et al. (2011) looked at the effect of mitragynine on behavior in zebrafish going through withdrawal after chronic morphine exposure. The effects of Mitragynine on morphine-withdrawn zebrafish.
Hallucinogenic drugs (psychedelics) have a growing significance in biopsychiatric research. Zebrafish are a popular animal model and seem highly sensitive to various drugs of abuse.
Zebrafish behavioral research has grown by leaps and bounds, and behavioral paradigms are being developed with the aim of better understanding mechanisms that might underlie aberrant behavioral phenotypes.
It was at the Society for Neuroscience last November that I was invited to speak at the second annual LAZEN meeting held last December in Porto Alegre, Brazil.
Zebrafish are increasingly swimming into the view of large-scale drug screening projects. Behavioral screens can be used as a first-line detection tool for new drug effects, and their popularity continues to grow.
Zebrafish is the new rat. Or mouse. More and more rodents in the lab are being replaced by these nifty little striped fish. They are easy to maintain, reproduce and develop rapidly.