Washington, D.C., United States - On Saturday, Maarten Loos presented the poster 'Longitudinal cognitive testing in mouse models of Aβ and Tau toxicity using an automated CognitionWall task'. In our Noldus booth, we're joined by Bastijn Koopmans and Maarten Loos to further explain the CognitionWall task and the use of the PhenoTyper home cage system. The poster attracted a lot of attention Saturday morning.
Go to Sylics.com if you'd like more information about the company and its products and services.
The exhibit hall opened on Sunday, and we've already met so many customers from around the world! This Neuroscience annual convention is the best place for us to connect with the research community. It is always great to talk about upcoming research projects and the opportunities that our solutions might offer to researchers.
Automated home-cage (PhenoTyper)-based task
Yesterday, in the theme Motivation and Emotion I came across two posters from the Center for Addiction and Mental Health (Toronto, Canada). Thomas Prévôt, PhD explained how they set out to characterize potential key features in the onset of pathological state. They assessed chronic restraint stress effects on anxiety-like behavior (response to a 1h spotlight stressor in home cage-like setting), anhedonia-like deficits (reduced sucrose consumption) and coat deterioration. Their PhenoTypers are being used back-to-back to facilitate this research. They are an innovative lab working on improving methods to be able to get better results.
With this research Prévôt et al. confirm that chronic stress is a multiphasic process where time-dependent cell-specific alterations are linked to various behavioral outcomes. Their research done in home cages reduces the impact that other stress factors have on the outcomes of the research. Since the mice are not disturbed in any other way, the researchers can be sure that the stress is related to the stressor (light) used in the study.
- Linking dynamic GABAergic, astroglial and synaptic dysfunctions to stress-induced depressive-like endophenotype: Importance of astroglial integrity - *T. D. PREVOT1, K. A. MISQUITTA1,2, C. J. FEE1,2, D. NEWTON1,2, H. OH1,3, E. SIBILLE1,2,3, M. BANASR1,2; 1Ctr. For Addiction and Mental Hlth., Toronto, ON, Canada; 2Dept. of Pharmacol., 3Dept. of Psychiatry, Univ. of Toronto, Toronto, ON, Canada
- Acute and chronic chemogenetic silencing of somatostatin-expressing GABA interneurons induces rapid, robust, and lasting elevation of depressive- and anxiety-like behaviors - C. J. FEE1,2, K. MISQUITTA1,2, R. BRAD1, T. D. PREVOT1, M. BANASR1, E. SIBILLE1,2,3; 1Ctr. For Addiction and Mental Hlth., Toronto, ON, Canada; 2Dept. of Pharmacol. & Toxicology, 3Dept. of Psychiatry, Univ. of Toronto, Toronto, ON, Canada
Yesterday we had a World Premiere in our booth! Prof. Pierre-Majorique Léger and Prof. Sylvain Sénécal presented for the first time their cloud-based lab management and analytics platform for triangulated human-centered research at the Society for Neuroscience.
Prof. Pierre-Majorique Léger and Prof. Sylvain Sénécal presented PhotoBooth
In a clear example they showed that combining data and visualizing it in an attractive way helps designers make better applications: They showed a recipe on a website, eye tracking revealed that people focus mostly on the text. The emotion data showed positive valence for the picture of the lasagna and negative valence for the text. By combining eye tracking and emotion data, you can provide a UX/application designer with better insights.
If you’re interested in learning more, please have a look at the Photobooth project or come by booth 1229 at #sfn17