motor-coordination-muscular-dystrophy

Testing motor coordination in a mouse model with muscular dystrophy

Muscular Dystrophy is a broad group of diseases recognized by the loss of muscle mass and strenght. Researchers tried to discover if gene therapy strategies can help with reducing symptoms.
parkinsons-disease-research

Parkinson's disease research - Relevant measures in pre-clinical studies

Parkinson’s disease: the neurodegenerative disorder that affects mobility in a life-changing way. Learn more about relevant measures in pre-clinical studies.
autistic-mice-cerebellum

Autistic mice have motor learning difficulties specific to the cerebellum

Autism is often associated with social behavior deficits and repetitive behaviors. However, motor abnormalities are also a part of the behavioral spectrum. Recent studies have implicated the cerebellum.
study-ataxia

How to study ataxia

Ataxia is a common problem in Parkinson’s disease (PD), and many early onset Alzheimer’s disease patients (AD) also deal with it. Now there is a non-invasive test for mouse models.
alzheimers-groundbreaking-research

Alzheimer's: prevent instead of cure?

Alzheimer’s disease (AD) is a huge public health issue as it affects a large part of the aging population. Neuropathology is studied primarily in the end stages of the disease. What about prevention?
10-studies-alzheimers-parkinsons

10 behavioral studies on Alzheimer’s and Parkinson’s

This blog post features 10 interesting studies that use innovative techniques to study models of AD and PD and important underlying neuronal mechanisms.
mice-cerebellar-plasticity

How to really challenge mice cerebellar plasticity

Jan-Willem Potters used the ErasmusLadder in his thesis research to study the role of specific mutations of plasticity in the cerebellar microcircuit of mice.
motor-functioning-mice

Walking the ladder: testing the cellular source of motor functioning in mice

The cerebellum, our “little brain”, is all about motor control; more specifically, it’s about coordination, precision, and timing.