CatWalk: the next step in gait analysis

Guido Koopmans (Erkrath, Germany)
Quantitative gait analysis is useful in objective assessment of walking ability as well as identifying the underlying causes for walking abnormalities in patients with cerebral palsy, Parkinson disease, stroke, head or spinal cord injury, and other neuromuscular problems. Over the years many different methods are developed to analyze gait in laboratory animals, ranging from scoring spontaneous open field locomotion to more sophisticated methods using contact electrode recordings, footprint analysis, kinetics, 2D and 3D kinematics, and CatWalk™. The current research focuses on CatWalk as a method to analyze and quantify locomotion in a model of spinal cord injury (SCI). The parameters measured by CatWalk, in particular measures for coordination, are used to test the behavioral implications of voluntary locomotor training induced by enriched housing facilities.

Analysis of motor function using CatWalk XT after spinal cord injury

Catwalk™ XT gait analysis can be used to analyze static and dynamic parameters of gait in mice and rats. In the study described in this user report, we used CatWalk XT gait analysis to monitor and quantify gait of spinal cord injured rats after treatment with vascular endothelial growth factor (VEGF).