ErasmusLadder references

This is a selection of publications that mention the use of ErasmusLadder. If you feel your publication should be on this list, please let us know at

Sathyanesan, A.; Gallo, V. (2018). Cerebellar contribution to locomotor behavior: A neurodevelopmental perspective. Neurobiology of learning and memory, doi: 10.1016/j.nlm.2018.04.016.

Seungmin Ha, Dongwon Lee, Yi Sul Cho, Changuk Chung, Ye-Eun Yoo, Jihye Kim, Jiseok Lee, Woohyun Kim, Hyosang Kim, Yong Chul Bae, Keiko Tanaka-Yamamoto and Eunjoon Kim (2016). Cerebellar Shank2 Regulates Excitatory Synapse Density, Motor Coordination, and Specific Repetitive and Anxiety-Like Behaviors, Journal of Neuroscience, 36 (48),12129-12143.

Peter, S.; ten Brinke, M.M.; Stedehouder, J.; Reinelt, C.M.; Wu, B.; Zhou, H.; Zhou, K.; Boele, H.; Kushner, S.A.; Lee, M.G.; Schmeisser, M.J.; Boeckers, T.M.; Schonewille, M.; Hoebeek, F.E.; De Zeeuw, C.I. (2016). Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice. Nature Communications, 7, 12627.

De Zeeuw, C.I.; Hoogland, T.M. (2015) Reappraisal of Bergmann glial cells as modulators of cerebellar circuit functionFrontiers in Cellular Neuroscience, doi 10.3389/fncel.2015.00246

Marques, A.R.A.; Aten, J.; Ottenhoff, R. van; Roomen, C.P.A.A.; Herrera Moro, D.; Claessen, N.; Vinueza Veloz, M.F.; Zhou, K.; Lin, Z.; Mirzaian, M.; Boot, R.G.; De Zeeuw, C.I.; Overkleeft, H.S.; Yildiz, Y.; Aerts, J.M.F.G. (2015) Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice. PLoS ONE, 10(8): e0135889. doi:10.1371/journal.pone.0135889

Vinueza Veloz, M.F. (2015). Cerebellar control of locomotion in health and disease. Erasmus University Rotterdam. Retrieved from

Sepulveda-Falla, D.; Barrera-Ocampo, A.; Hagel, C.; Korwitz, A.; Vinueza-Veloz, M.F.; Zhou, K.; Schonewille, M.; Zhou, H.; Velazquez-Perez, L.; Rodriguez-Labrada, R.; Villegas, A.; Ferrer, I.; Lopera, F.; Langer, T.; De Zeeuw, C.I.; Glatzel, M. (2014). Familial Alzheimer's disease-associated presenilin-1 alter cerebellar activity and calcium homeostasisThe Journal of Clinical Investigation124(4), 1552-1567.

Vinueza Veloz, M.F.; Zhou, K.; Bosman, L.W.J.; Potters, J.-W.; Negrello, M.; Seepers, R.M.; Strydis, C.; Koekkoek, S.K.E.; De Zeeuw, C.I. (2014). Cerebellar control of gait and interlimb coordinationBrain Structure and Function, doi: 10.1007/s00429-014-0870-1. Read about this study on our behavioral research blog

Baudouin, S.J.; Gaudias, J.; Gerharz, S.; Hatstatt, L.; Zhou, K.; Punnakkal, P.; Tanaka, K.F.; Spooren, W.; Hen, R.; De Zeeuws, C.I.; Vogt, K.; Scheiffele, P. (2012) Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autismScience338, 128-132.

Boele, C.P., Roelofs R., Koekkoek SKE & De Zeeuw C.(2013) Automated assessment of motor learning and motor performance using the Erasmus Ladder - a new method for phenotyping of mouse mutants. Poster, IBANGS conference 2013.

Cupido, A. (2009). The Erasmus Ladder: a new, automated system for precise phenotyping of motor behavior in mice. PhD Thesis, Erasmus University Rotterdam (Chapter 2). 

Galliano, E.; Gao, Z.; Schonewille, M.; Todorov, B.; Simons, E.; Pop, A.S.; D’Angelo, E.; Maagenberg, A.M.J.M.; Hoebeek, F.E.; De Zeeuw, C. (2013). Silencing the Majority of Cerebellar Granule Cells Uncovers Their Essential Role in Motor Learning and Consolidation. Cell Reports, 3, 1239-1251.

Saab, A.S.; Neumeyer, A.; Jahn, H.M.; Cupido, A.; Simek, A.A.M.; Boele, H.-J.; Scheller, A.; Le Meur, K.; Götz, M.; Monyer, H.; Sprengel, R.; Rubio, M.E.; Deitmer, J.W., De Zeeuw, C.I.; Kirchhoff, F. (2012) Bergmann glial AMPA receptors are required for fine motor coordination. Science337, 749-753.

Schonewille, M.; Gao, Z.; Boele, H.-J.; Vinueza Veloz, M.F.; Amerika, W.E.; Simek, A.A.M.; De Jeu, M.T.; Steinberg, J.P.; Takamiya, K.; Hoebeek, F.E.; Linden, D.J.; Huganir, R.L.; De Zeeuw, C.I. (2011). Reevaluating the Role of LTD in Cerebellar Motor Learning. Neuron, 70, 43-50.

Venueza Veloz, M.F.; Buijsen, R.A.M.; Willemsen, R.; Cupido, A.; Bosman, L.W.J.; Koekkoek, S.K.E.; Potters, J.W.; Oostra, B.A.; De Zeeuws, C.I. (2012) The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice. Genes, Brain and Behavior, 11, 325–331.