Zebrafish offer an interesting model for cardiovascular research; their heart is the first organ to develop and its development is similar to that of the human heart. In addition, fish do not depend on the cardiovascular system for survival during embryogenesis.

Toxicology and pharmacology

When developing new drugs, negative side effects on the cardiovascular system are often a reason for the discontinuation of projects. Measuring the heart rate is an important read-out in toxicological, pharmacological, and other studies on the cardiovascular system using larval zebrafish.

Measuring heart rate and inter-beat interval

Traditional methods like manual counting (using a stopwatch), micro pressure systems, Laser Doppler microscopy, and electrocardiograms are labor-intensive and require specific training. This makes them very expensive. 

Combining the advantage of zebrafish larvae being transparent with the latest developments in video analysis technologies, results in a much more efficient and less invasive method.

Easy measurement

DanioScope is a software program that does exactly that, offering a very straight-forward tool to accurately and efficiently assess the heart rates of multiple zebrafish larvae simultaneously. There is no specific training required. 

Zebrafish research with DanioScope

If you are interested in a scope of zebrafish embryo and larvae parameters such as embryo activity, cardiovascular measurements, morphology, and gut and blood flow, then DanioScope is just what you need. This software tool is based on video files and images, and it offers an easy-to-use and non-invasive way to study your zebrafish.

DanioScope offers tools to measure embryo activity, cardiology measurements, blood and gut flow, and morphology.

Free demo