Open field

The open field is a generally accepted and straight-forward test to investigate anxiety-related and exploratory behavior of rodents. The open field is an empty test arena, usually round or square, in which the animal’s activity is measured. The amount of time spent close to the wall (an anxiety-like response referred to as thigmotaxis) versus the amount of time spent in, and frequencies of visits to, the inner zone are measured. Additionally, general locomotor behavior (total distance moved) is often taken into account.

For a complete solution, combine a PhenoTyper basic cage or an open field with EthoVision XT.

Examples of parameters
  • Percentage of time spent in the outer zone as a measure for thigmotaxis.
  • Latency to visit the center zone as a measure of fear.
  • Percentage of time spent elongated.
  • Number of square entries in each five minutes period.
Components

Optional components

Typical components

Optional components

Selected publications
  • Bergh, F., van den; Spronk, M.; Ferreira, L.; Bloemarts, E.; Groenink, L.; Olivier, B.; Oosting, R. (2007). Relationship of delay aversion and response inhibition to extinction learning, aggression, and sexual behaviour. Behavioural Brain Research, 175, 75-81.
  • Bouwknecht, J.; Spiga, F.; Staub, D.; Hale, M.; Shekhar, A.; Lowry, C. (2007). Differential effects of exposure to low-light or high-light open-field on anxiety-related behaviors: Relationship to c-fos expression in serotonergic and non-serotonergic neurons in the dorsal raphe nucleus. Brain Research Bulletin, 72, 32-43.