Alzheimer's and Parkinson's
Neurodegenerative diseases such as Alzheimer's and Parkinson's are often characterized by changes in cognition, locomotion, and even anxiety. Measuring these outputs in animal (disease) models is crucial for understanding the underlying mechanisms of these diseases, for applications in humans.
A 5-HT1A agonist and NMDA antagonist against Parkinson’s disease
Reducing side effects of L-Dopa with 5-HT1A receptor agonists can improve motor activity in a Parkinson’s disease model when combined with NMDA antagonists.
A plant-based treatment for Alzheimer's disease?
Researchers are constantly looking for new ways to treat Alzheimer's disease. Can Dioscin, a plant-based steroid, decrease the symptoms in mice?
New method for early detection of Alzheimer's disease
The color x-maze can be used to pick up symptoms of Alzheimer's disease in AD-mice months before traditional cognitive tests.
Part 2: How researchers use the Morris water maze to find treatments for AD
In this second part of a two-part mini series, we highlight two more studies on potential Alzheimer’s disease treatments that are investigated using a Morris water maze.
How researchers use the Morris water maze to find treatments for Alzheimer's
In this first part of a two-part mini series, we highlight how potential Alzheimer’s disease treatments are being investigated using a Morris water maze.
What is the Barnes maze? A dry-land environment for testing learning and memory
The Barnes maze is a behavioral paradigm for testing learning and memory in rodents models for autism spectrum disorder, Alzheimer’s disease and ageing. How does it compare to the Morris water maze?
Can caffeine prevent Alzheimer's?
What is the most popular drug in the world? It’s not alcohol, cannabis, or cocaine, but something most of us start with each day. Coffee; or, more specifically: caffeine.
How doing exercises counteracts the effects of Alzheimer’s disease
Recent research has shown that rats induced with Alzheimer’s disease suffered less from the effects of the disease when subjected to exercise.
How mice regain their memory: Betaine against Alzheimer’s Disease
As a potential Alzheimer medicine, betaine was tested on an AD animal model in a novel object recognition test. Using video tracking, scientists studied the influence of betaine and betaine transporter on mouse memory.
Diazepam in the battle against Alzheimer’s
Scientists have found out that a low dose of the tranquilizer diazepam reduces the breakdown of neurons, seen in the development of Alzheimer’s disease.