The open field test is a locomotor, exploratory and/or anxiety test. Can we measure all these behaviors in a simple enclosed arena? This is exactly what we talk about in this blog, and the discussion surrounding this.
Behavioral cores benefit universities as well as science in general. Recent cases show improved reproducibility of tests and protocols to assess a more complex phenotype of model animals.
A couple of months ago, we had the pleasure to visit the University of Groningen to record a customer success story.
Bank voles are often exposed to predator odor and alarm pheromones. This perceived predation risk may cause cross-generational behavior changes, which seem to be context-dependent on their in utero exposure.
Silymarin is a substance that works as an antioxidant, is anti-inflammatory and increases BDNF levels. After supplementing silymarin to diabetic rats, typical diabetes symptoms were greatly improved.
Gulf War Illness (GWI) is potentially caused by organophosphate exposure. Through behavioral experiments, using a DFP rat model, researchers tested levetiracetam as a potential cure.
Gut microbes can increase or decrease typical autism spectrum disorder behavior (stereotypies, social behavior, locomotion, and communication) via metabolites and influencing alternative gene splicing.
Scientists have found out that a low dose of the tranquilizer diazepam reduces the breakdown of neurons, seen in the development of Alzheimer’s disease.
Preterm birth is a major problem in neonatal healthcare. Erik van Tilborg developed a new animal model to closely mimic this clinical situation, an important step in finding new treatment options.