Like rats and mice, fruit flies avoid open spaces and stay close to physical borders. In rats and mice this is caused by fear to be out in the open and preference for close contact with borders.
Nausea is a prominent factor influencing the quality of life for patients undergoing chemotherapy. That is why it is useful to study the nauseating side effects of therapies or the anti-nauseating potential of drugs.
Recent work done by Khor et al. (2011) looked at the effect of mitragynine on behavior in zebrafish going through withdrawal after chronic morphine exposure. The effects of Mitragynine on morphine-withdrawn zebrafish.
Hallucinogenic drugs (psychedelics) have a growing significance in biopsychiatric research. Zebrafish are a popular animal model and seem highly sensitive to various drugs of abuse.
Bed bugs are on the rebound in developed countries. Traditionally, bed bugs are controlled with pesticides. However, traps with attractive human body odors are a promising alternative.
The Morris water maze and EthoVision, a validated solution to investigate learning and memory in rats and mice.
Zebrafish are increasingly swimming into the view of large-scale drug screening projects. Behavioral screens can be used as a first-line detection tool for new drug effects, and their popularity continues to grow.
Recently Lucas Noldus was interviewed for a technology feature in Nature; “Inside the minds of mice and men” by Monya Baker.
Zebrafish is the new rat. Or mouse. More and more rodents in the lab are being replaced by these nifty little striped fish. They are easy to maintain, reproduce and develop rapidly.