Behavioral effects of optogenetically induced myelination in mice

Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases.

How to study ataxia

Ataxia is a common problem in Parkinson’s disease (PD), and many early onset Alzheimer’s disease patients (AD) also deal with it. Now there is a non-invasive test for mouse models.

Alzheimer's: prevent instead of cure?

Alzheimer’s disease (AD) is a huge public health issue as it affects a large part of the aging population. Neuropathology is studied primarily in the end stages of the disease. What about prevention?

Gait research: let your animals walk freely

Researchers use different ways to analyze gait in animals. In what instances would a study benefit from a system that is based on voluntary walking?

10 behavioral studies on Alzheimer’s and Parkinson’s

This blog post features 10 interesting studies that use innovative techniques to study models of AD and PD and important underlying neuronal mechanisms.

Parkinson’s & gait impairment: comparing rats and humans

Gait impairment is one of the most prominent symptoms of Parkinson's disease. For good research you need good models and good tests.

Using CatWalk gait analysis to study monoarthritis in mice

Researchers are always looking for new ways to alleviate symptoms of arthritis. The CatWalk XT has been shown to be very useful in research involving arthritis in rodent models.

Going the distance - and why it matters in gait analysis

A footprint, that is. With CatWalk XT, you can extract a lot of information from just one footprint. In this post, I am taking it a step further by talking about the relationship between prints.

Recent applications of locomotor and gait analysis

Stem cell research is a promising area of research for spinal cord injury. With 1,25 million individuals suffering from chronic spinal cord injury in the US alone, new treatment approaches are necessary.