The Hypothalamus is involved in locomotion? Complex dopamine circuitry uncovered
By measuring locomotion and investigating dopaminergic neurons, complex dopamine circuitry is uncovered. How are amphetamine and our biological clock involved in this?
Better together or happier apart? The effects of housing on stress in mice
Does housing mice on their own affect animal welfare and reduce experimental validity? How was EthoVision XT video tracking software used to automate this investigation?
3 high impact papers about measuring anxiety in the Elevated Zero Maze
The elevated zero maze (EZM) is a variation on the elevated plus maze (EPM) and was created to eliminate the center region of the EPM. This blog highlights 3 studies that use the EZM to test for anxiety-like behavior
The open field test: A staple in behavioral batteries
The open field test is a locomotor, exploratory and/or anxiety test. Can we measure all these behaviors in a simple enclosed arena? This is exactly what we talk about in this blog, and the discussion surrounding this.
A critical view on the Forced swim test
The forced swim test (FST), a staple in depression research, has been under discussion for a while. What is the FST? How is it used? And why is it under discussion? Here we share our view on this topic
Robust and reliable: Measuring anxiety in the Elevated plus maze
Screening of anxiety-like behavior in the elevated plus maze becomes more reliable with Ethovision XT combined with the standardization of testing parameters and common practices.
Taking opioids during pregnancy: short- and long-term consequences in rats
Women worldwide are suffering from opioid addiction. Many receive so-called opioid-maintenance therapy using buprenorphine, but consequences for both mother and baby are largely unknown.
Antidepressants during pregnancy: effects on offspring social behavior
Many depressed women struggle with this: can I use antidepressants during pregnancy? The lab of Jocelien Olivier studies the effects of SSRI's on offspring behavior in an animal model.
Depressed with a failing reward system: social stress disrupts brain waves
Chronic social stress has a huge impact on well-being. Gamma oscillations have been found to be an electrophysiological link between social stress and reward processing.
Is a unique calcium regulating mechanism a cause of Gulf War Illness?
Gulf War Illness (GWI) is potentially caused by organophosphate exposure. Through behavioral experiments, using a DFP rat model, researchers tested levetiracetam as a potential cure.