Our lab studies the Neuronal Ceroid Lipofuscinoses (NCLs) or Batten disease, which are a group of progressive and genetically inherited neurodegenerative diseases that affect children and young adults.
At the Dr. Michael Fehlings' lab, they are on a quest to find out what exactly causes the lower success rate of delayed surgery in cervical myelopathy.
Heta Svard from Orion Pharma studies pain and neurological disorders and resports on recent research.
Letting animals walk freely in gait research. At Noldus, we strongly believe this is the way to go, so that is how our CatWalk XT system works.
Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases.
Researchers use different ways to analyze gait in animals. In what instances would a study benefit from a system that is based on voluntary walking?
Gait impairment is one of the most prominent symptoms of Parkinson's disease. For good research you need good models and good tests.
Jan-Willem Potters used the ErasmusLadder in his thesis research to study the role of specific mutations of plasticity in the cerebellar microcircuit of mice.
Researchers are always looking for new ways to alleviate symptoms of arthritis. The CatWalk XT has been shown to be very useful in research involving arthritis in rodent models.
Traditionally, there are two fundamentally different ways to analyze gait in animals. One can either observe or measure gait in an unrestricted manner, or in a forced manner, as seen when using a treadmill or treadwheel.