Heta Svard from Orion Pharma studies pain and neurological disorders and resports on recent research.
Letting animals walk freely in gait research. At Noldus, we strongly believe this is the way to go, so that is how our CatWalk XT system works.
Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases.
Researchers use different ways to analyze gait in animals. In what instances would a study benefit from a system that is based on voluntary walking?
Gait impairment is one of the most prominent symptoms of Parkinson's disease. For good research you need good models and good tests.
Jan-Willem Potters used the ErasmusLadder in his thesis research to study the role of specific mutations of plasticity in the cerebellar microcircuit of mice.
Researchers are always looking for new ways to alleviate symptoms of arthritis. The CatWalk XT has been shown to be very useful in research involving arthritis in rodent models.
Traditionally, there are two fundamentally different ways to analyze gait in animals. One can either observe or measure gait in an unrestricted manner, or in a forced manner, as seen when using a treadmill or treadwheel.
The ability to recognize harmful situations and respond accurately is important for the survival of any animal. In order to respond to these situations the animal must be able to learn, remember, and alter its behavior.
I have written two blog posts about static gait parameters. Now it’s time to talk about all four paws, and the time based relationships between them. If you ask me, we’ve been saving the best blog post for last!