Gait and locomotion studies

Gait and locomotion studies in animals uncover links between movement patterns and various neurological or motor disorders. These studies provide invaluable insights for the therapeutic development of treatments and cures for these disorders.

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Vestibulopathy: movement and balance issues investigated in rats

It is hard to diagnose vestibulopathy, so a rat model was developed to study the progress of symptoms, from day one to day 30 after ear injury. Results can improve future human diagnosis and therapy options.
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A new sensory and motor scale for the CIA arthritis mouse model

Dr. Bonnefont and her colleagues at IRMB in France just recently proposed a new ArthriSM scale to predict motor and sensory functional deficits in arthritis mouse model. Read more about it in her blog post!
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CatWalk XT: Valid tool for objective gait analysis in TBI mice model

Many people suffer from TBI and consequently also long-term gait and motor function deficits. For this reason, functional outcome became the focus when developing new treatment strategies for TBI.
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Gait analysis after a bone fracture

Recovery after a bone fracture is more than just healing bone and soft tissue. Research on gait analysis is necessary in order to improve knowledge about bone regeneration and rehabilitation after lower extremity fractures!
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Assessing motor outcome in rats with peripheral nerve injury

At LBI Trauma, CatWalk XT is one of the most important tools to evaluate functional recovery in different animal models. Read more about what they found to be key factors when studying motor performance in rats with femoral nerve injury.
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Traumatic Brain Injury: effects on the brain and motor coordination

Do you think of wearing a helmet while skiing, cycling or horseback riding? Read more about how the brain is affected after the head injury and how you can examine locomotion in a mouse model with TBI.
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Testing motor coordination in a mouse model with muscular dystrophy

Muscular Dystrophy is a broad group of diseases recognized by the loss of muscle mass and strenght. Researchers tried to discover if gene therapy strategies can help with reducing symptoms.
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How to best assess pain-related behaviors in preclinical studies

Most humans can tell you they’re in pain. However, assessing pain sensitivity in rodents during preclinical studies is a challenge.
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Assessing gait in a mouse model for Leigh Syndrome

There is an unmet medical need to develop clinical effective treatments for Leigh Syndrome and other mitochondrial diseases. Today, Dr. de Haas shares some of her research insights.
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Gait analysis at the PSDL using CatWalk

Our lab studies the Neuronal Ceroid Lipofuscinoses (NCLs) or Batten disease, which are a group of progressive and genetically inherited neurodegenerative diseases that affect children and young adults.