Brown mouse with outstretched tail
As a potential Alzheimer medicine, betaine was tested on an AD animal model in a novel object recognition test. Using video tracking, scientists studied the influence of betaine and betaine transporter on mouse memory.
Researching learning and memory
Scientists have found out that a low dose of the tranquilizer diazepam reduces the breakdown of neurons, seen in the development of Alzheimer’s disease.
Radial Arm Maze
The radial arm maze is an apparatus consisting of a circular center compartment from which 8 equally spaced «arms» extend. Researchers use it to measure two forms of memory known as “reference memory” and “working memory.”
alheimer model mice
Plaques and tangles… those of you even remotely familiar with Alzheimer’s disease (AD) will immediately recognize these hallmarks. But they are linked to familial AD, while sporadic AD is far more common.
cognitionwall
Sylics recently introduced CognitionWall, a new paradigm for discrimination learning in the home cage that avoids the necessity for food restriction and handling in learning tests.
olfactory memory
When you get used to something, after a while you might not notice it anymore. Like a sent. The lab of Justus Verhagen investigated sniffing behavior with video tracking.
We sleep a large portion of our lives. And now researchers have proven that it can heal the brain.
A new model for POCD in rats
This week we have a guest post by Iris Hovens. She has done some really interesting research into the consequences of surgery in terms of reduced memory and concentration problems.
home cage testing
Mouse models are essential for neuroscience research. Many tests are susceptible to bias. Home cage testing provides a number of solutions.
Alzheimer's treatment
Xu Liu and colleagues recently investigated the effects of Ginkgo biloba extract on a mouse model for Alzheimer’s disease (AD).
Zebrafish
The zebrafish (Danio rerio) is increasingly being used as model in behavioural, neurobiological and genetic research.