This week we have a guest post by Iris Hovens. She has done some really interesting research into the consequences of surgery in terms of reduced memory and concentration problems.
Mouse models are essential for neuroscience research. Many tests are susceptible to bias. Home cage testing provides a number of solutions.
Xu Liu and colleagues recently investigated the effects of Ginkgo biloba extract on a mouse model for Alzheimer’s disease (AD).
The zebrafish (Danio rerio) is increasingly being used as model in behavioural, neurobiological and genetic research.
Rearing animals specifically for behavioral research is a very common practice. However, the results from behavioral studies with laboratory animals should be interpreted with care.
Novel object recognition is one of the most commonly used behavioral tests on laboratory rodents. It is also easily automated with video tracking software. Want to know how?
Often in animal research, animals with a certain genetic alteration are compared to a “wild-type”. One might assume that there is no differences between wild-types, but many different strains of wild-type animals are used.
On a yearly basis, an estimated 20.000 individuals are diagnosed with primary brain tumors in the United States alone. About ten times that number of patients will receive treatment for primary or metastatic brain cancer.
In the beginning of this year I wrote a post about the Morris water maze test, a popular and well-validated paradigm to study learning and memory in rats and mice.
A great example of optogenetics in behavioral studies is the work of Dr. Kravitz and Dr. Kreitzer at the Kreitzer lab (currently, Kravitz works at the NIDDK in Bethesda). Let me tell you about it.