A commonly used assay for assessment of fear in animals is the novel environment test.In this test, an animal is placed in an arena for a particular time period and behaviors are scored.
Here are six recommendations the authors list to improve the translational and predictive value of behavioral readouts.
Scientists have been performing open field tests for quite some time now. Over the years it has become one of the most popular tests in rodent behavioral research. So what’s not to love?
We all know of animals that are able to regenerate: lizards that grow back their tails, flatworms that can grow into new worms when cut in half. Zebrafish have this special ability as well.
Zebrafish. This little fish is a vertebrate, and a relatively complex one. Looking at the major neurotransmitters and hormones that are investigated in neuroscience, they are as good of a model as many mammalian species.
Some disorders cannot simply be diagnosed with a blood test or tissue-culture. Autism Spectrum Disorder (ASD) is a good example; its diagnosis relies upon behavioral tests and questionnaires.
As humans, we help each other because it is the right thing to do. We help our friends and our family. And of course we help strangers as well. Right?
Anxiety. It is nature’s way to keep us out of harm’s way, so it is a useful emotion. At times, though, it can also be overwhelming. For some, it gets out of control, irrational, and even disabling.
Did you know that Alzheimer’s and diabetes are linked? Patients with diabetes have an increased risk for Alzheimer’s disease (AD) and patients with AD show impaired insulin function and glucose metabolism.
If zebrafish are the new mice, guinea pigs might be the new rats. Guinea pigs differ from mice and rats, and that just might make them more suitable due to the fact that these results are more easily translated to humans.