Epilepsy is more than seizures; behavioral changes that occur in between seizures are rarely assessed. A new home cage study from the Baylor College of Medicine aims to change this.
Rodent social behavior is important in research on neuropsychiatric disorders, but major limitations hamper progress.
Sylics recently introduced CognitionWall, a new paradigm for discrimination learning in the home cage that avoids the necessity for food restriction and handling in learning tests.
Mouse models are essential for neuroscience research. Many tests are susceptible to bias. Home cage testing provides a number of solutions.
Prof. Dr. Berry M. Spruijt recently retired from his position at Utrecht University. I had the honor of attending the symposium that was organized to reflect on and celebrate his career.
Traditional standard tests with rats or mice are carried out immediately after human interference. Therefore, the behavior of the animals may not be natural and spontaneous.
If zebrafish are the new mice, guinea pigs might be the new rats. Guinea pigs differ from mice and rats, and that just might make them more suitable due to the fact that these results are more easily translated to humans.
The most common psychiatric disorders are mood and anxiety related. However, the underlying mechanisms of these diseases are still largely unknown. This complicates the development of effective treatment and drugs.
The ability to recognize harmful situations and respond accurately is important for the survival of any animal. In order to respond to these situations the animal must be able to learn, remember, and alter its behavior.
Behavior of laboratory rodents is often studied in well-controlled, simple experiments, in an environment that is fundamentally different from the animal’s home cage.