The open field test: A staple in behavioral batteries
The open field test is a locomotor, exploratory and/or anxiety test. Can we measure all these behaviors in a simple enclosed arena? This is exactly what we talk about in this blog, and the discussion surrounding this.
Vestibulopathy: movement and balance issues investigated in rats
It is hard to diagnose vestibulopathy, so a rat model was developed to study the progress of symptoms, from day one to day 30 after ear injury. Results can improve future human diagnosis and therapy options.
Getting robust results: one zebrafish is not like the other
Zebrafish larvae locomotor behavior often has a high variability, which can have a big impact on your results. Still, it is one of the most used parameters. So how can you make your study more robust?
Gait analysis after a bone fracture
Recovery after a bone fracture is more than just healing bone and soft tissue. Research on gait analysis is necessary in order to improve knowledge about bone regeneration and rehabilitation after lower extremity fractures!
Traumatic Brain Injury: effects on the brain and motor coordination
Do you think of wearing a helmet while skiing, cycling or horseback riding? Read more about how the brain is affected after the head injury and how you can examine locomotion in a mouse model with TBI.
Diazepam in the battle against Alzheimer’s
Scientists have found out that a low dose of the tranquilizer diazepam reduces the breakdown of neurons, seen in the development of Alzheimer’s disease.
Parkinson's disease research - Relevant measures in pre-clinical studies
Parkinson’s disease: the neurodegenerative disorder that affects mobility in a life-changing way. Learn more about relevant measures in pre-clinical studies.
Autistic mice have motor learning difficulties specific to the cerebellum
Autism is often associated with social behavior deficits and repetitive behaviors. However, motor abnormalities are also a part of the behavioral spectrum. Recent studies have implicated the cerebellum.
How to let rats run perfectly
Letting animals walk freely in gait research. At Noldus, we strongly believe this is the way to go, so that is how our CatWalk XT system works.
Behavioral effects of optogenetically induced myelination in mice
Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases.