open-field-behavioral-staple

The open field test: A staple in behavioral batteries

The open field test is a locomotor, exploratory and/or anxiety test. Can we measure all these behaviors in a simple enclosed arena? This is exactly what we talk about in this blog, and the discussion surrounding this.
vestibulopathy-investigated-rat-model

Vestibulopathy: movement and balance issues investigated in rats

It is hard to diagnose vestibulopathy, so a rat model was developed to study the progress of symptoms, from day one to day 30 after ear injury. Results can improve future human diagnosis and therapy options.
robust-results-intra-individual-locomotor-patterns-zebrafish-larvae

Getting robust results: one zebrafish is not like the other

Zebrafish larvae locomotor behavior often has a high variability, which can have a big impact on your results. Still, it is one of the most used parameters. So how can you make your study more robust?
gait-analysis-bone-fracture

Gait analysis after a bone fracture

Recovery after a bone fracture is more than just healing bone and soft tissue. Research on gait analysis is necessary in order to improve knowledge about bone regeneration and rehabilitation after lower extremity fractures!
tbi-effects-brain-motor-coordination

Traumatic Brain Injury: effects on the brain and motor coordination

Do you think of wearing a helmet while skiing, cycling or horseback riding? Read more about how the brain is affected after the head injury and how you can examine locomotion in a mouse model with TBI.
diazepam-alzheimers

Diazepam in the battle against Alzheimer’s

Scientists have found out that a low dose of the tranquilizer diazepam reduces the breakdown of neurons, seen in the development of Alzheimer’s disease.
parkinsons-disease-research

Parkinson's disease research - Relevant measures in pre-clinical studies

Parkinson’s disease: the neurodegenerative disorder that affects mobility in a life-changing way. Learn more about relevant measures in pre-clinical studies.
autistic-mice-cerebellum

Autistic mice have motor learning difficulties specific to the cerebellum

Autism is often associated with social behavior deficits and repetitive behaviors. However, motor abnormalities are also a part of the behavioral spectrum. Recent studies have implicated the cerebellum.
rats-run-perfectly

How to let rats run perfectly

Letting animals walk freely in gait research. At Noldus, we strongly believe this is the way to go, so that is how our CatWalk XT system works.
optogenetically-induced-myelination

Behavioral effects of optogenetically induced myelination in mice

Myelination, the ‘ensheathment’ of neurons, is essential to the functioning of the central and peripheral nervous systems. So it is not surprising that problems with myelination can lead to a number of crippling diseases.