Our lab studies the Neuronal Ceroid Lipofuscinoses (NCLs) or Batten disease, which are a group of progressive and genetically inherited neurodegenerative diseases that affect children and young adults.
Is it justified to use male mice only in behavioral studies, as many diseases affect men and women differently? This might be the most important argument to favor including female mice in certain studies.
How do mice act in complete darkness? Ann-Kristina Fritz and her colleagues ordered a large, round open field with IR backlight, custom made by Noldus, to investigate.
Plaques and tangles… those of you even remotely familiar with Alzheimer’s disease (AD) will immediately recognize these hallmarks. But they are linked to familial AD, while sporadic AD is far more common.
By a showing of hands: how many of you started this New Year with the resolution to get moving? Burn off those extra holiday calories, or finally really get in shape?
Optogenetics has been invaluable in many brain studies, chemogenetics has been a good non-invasive alternative. Magnetogenetics is the new kid on the block. Can it do better?
Today Marcelle Cline and Donna Cross are so kind to share their insights on testing TBI mice with the CatWalk XT system.
Serotonin is a busy neurotransmitter, influencing processes as memory, mood, emotion, appetite, and sexuality. A prime role for this neurotransmitter is social behavior, across a variety of species; humans, rodents, primates.
Aggressive behavior is adaptive for most species. But how is this aggressive behavior mediated in the brain? A recent study indicates that the hippocampus is a crucial neural component in mediating social recognition.
Jan-Willem Potters used the ErasmusLadder in his thesis research to study the role of specific mutations of plasticity in the cerebellar microcircuit of mice.