IR backlight in rodent behavioral testing
How do mice act in complete darkness? Ann-Kristina Fritz and her colleagues ordered a large, round open field with IR backlight, custom made by Noldus, to investigate.
Spatial and odor memory impaired mice – new model for Alzheimer’s
Plaques and tangles… those of you even remotely familiar with Alzheimer’s disease (AD) will immediately recognize these hallmarks. But they are linked to familial AD, while sporadic AD is far more common.
How obese mice get moving
By a showing of hands: how many of you started this New Year with the resolution to get moving? Burn off those extra holiday calories, or finally really get in shape?
Assessing motor deficits in mice following traumatic brain injury
Today Marcelle Cline and Donna Cross are so kind to share their insights on testing TBI mice with the CatWalk XT system.
Serotonin and social skills: how adult mice differ from juveniles
Serotonin is a busy neurotransmitter, influencing processes as memory, mood, emotion, appetite, and sexuality. A prime role for this neurotransmitter is social behavior, across a variety of species; humans, rodents, primates.
Revealing the secret social role of the CA2 hippocampus
Aggressive behavior is adaptive for most species. But how is this aggressive behavior mediated in the brain? A recent study indicates that the hippocampus is a crucial neural component in mediating social recognition.
How to really challenge mice cerebellar plasticity
Jan-Willem Potters used the ErasmusLadder in his thesis research to study the role of specific mutations of plasticity in the cerebellar microcircuit of mice.
A high-throughput method to screen natural behavior of mice
Traditional standard tests with rats or mice are carried out immediately after human interference. Therefore, the behavior of the animals may not be natural and spontaneous.
Walking the ladder: testing the cellular source of motor functioning in mice
The cerebellum, our “little brain”, is all about motor control; more specifically, it’s about coordination, precision, and timing.