Elevated plus maze

The elevated plus maze is another well-characterized behavioral
paradigm. The maze contains two open arms and two closed (wallsheltered)
arms. The test relies upon the animal’s natural tendency to
stay in enclosed spaces and their unconditioned fear for open spaces
and heights – anxious animals will spend more time in the closed
arms than less anxious animals.

A complete solution ideal for automated tracking includes this elevated plus maze and EthoVision XT.

 

Examples of parameters
  • Percentage of time spent in the open or closed arms.
  • Number of entries into each arm.
  • Latency to the first open arm entry.
  • Number of zone transitions from closed arm to center zone.
  • Total time spent immobile.
  • Percentage of time spent elongated.
Components

Optional components

Typical components

Selected publications
  • Burghardt, P.; Wilson, M. (2006). Microinjection of naltrexone into the central, but not the basolateral, amygdale blocks the
    anxiolytic effects of diazepam in the plus maze. Neuropsychopharmacology, 31, 122 7-12 40.
  • Jung, J.; Yoon, B.; Oh, H.; Ahn, J.; Kim, S.; Park, S-Y.; Ryu, J. (2006). Anxiolytic-like effects of Gastrodia elata and its phenolic
    constituents in mice. Biological & Pharmaceutical Bulletin, 29, 261-265.

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