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Webinar
No two mice alike: leveraging inter-individual variability in threat conditioning of inbred mice to model trait anxiety
Dr. Kovlyagina and her collaborators have developed a novel experimental and computational pipeline to operationalize trait anxiety in male and female inbred (C57BL6J) mice. For this webinar Dr. Kovlyagina will provide insight into the methodology of their pipeline and how EthoVision XT contributed to it.
Date | Thursday, 11 April 2024
Time | 4pm CEST / 10am EDT
Duration | 60 minutes
Summary
Personality and trait research in humans has identified trait anxiety as a major risk factor for developing mood and anxiety disorders. Traits, defined as consistent behavioral patterns within an individual across various contexts, necessitate evaluation through diverse tasks for effective classification. Dr. Kovlyagina and her co-authors developed a novel pipeline by combining the threat conditioning paradigm with prolonged retrieval session and classical anxiety tasks to elucidate a behavioral marker of trait anxiety in inbred mice. The resulting experimental and computational pipelines are designed to be easily adopted and utilize a mix of commercial and open-source solutions.
Dr. Irina Kovlyagina
Dr. Kovlyagina completed work on her doctoral thesis last year in the laboratory of Prof. Beat Lutz at Johannes Gutenberg University in Mainz, Germany. Her research focused on establishing a high throughput, translationally relevant model of trait anxiety.
Her previous experience includes development and characterization of ALS models at Johns Hopkins University and the University of Maryland in Baltimore, USA
Huib van den Heuvel
Huib van den Heuvel received his Masters in Animal Sciences at the University of Wageningen, The Netherlands. He specialized in animal behavior and specifically the use of sensors in quantifying behavior of chickens.
After his studies, Huib came to work at the marketing department of Noldus IT. Here he is responsible for writing and conceptualizing marketing materials for the animal market and especially PhenoTyper and CatWalk XT.