Increasing Reproducibility and Reliability of Novel Object Tests Through Standardization and Automation

white rat with a novel object

Join Alicia Brantley, PhD for a deep dive into her work involving novel object tests, the challenges associated with these protocols, and the solutions she is exploring to overcome these challenges, organized by Inside Scientific.

Date | Tuesday, March 30, 2021

Time | 8:00 am PT / 11:00 am ET / 5:00 pm CET 

Duration | 60 min


While many mouse behavioral assays are easily reproducible, novel object test protocols can vary greatly and can be difficult to reproduce due to the specificity of the objects, equipment, and techniques utilized by a particular lab.  In a behavioral core setting, this can be even more challenging due to the varying experience levels of investigators performing the task and quantifying the mouse-object interactions manually.  Updating novel object tests with new technological methods may be the key to increasing reproducibility and reliability in these tests.

Key Topics Include:

  • Defining novel object test procedures and goals
  • Understanding primary challenges to reproducibility in novel object tests
  • Successfully utilizing behavioral tracking software to increase reliability in novel object tests

Alicia Brantley

Alicia Brantley, PhD

Scientific Director
Mouse Behavior Core
Scripps Research, Florida Campus

Dr. Brantley is the Scientific Director of the Mouse Behavior Core at Scripps Research in Jupiter, Florida. In this role, Dr. Brantley uses her expertise to provide researchers at multiple institutes with insight, training, access, and support to better understand the neurobiology of behavior. She is also working to develop her own improved methods for quantitative assessment of behaviors. Dr. Brantley draws from more than 20 years of behavioral research experience in designing and validating behavioral assays for various rodent species.