European Autism Interventions
A Multicentre Study for Developing New Medications
EU-AIMS is the largest single project for autism in the world, and the largest for the study of any mental health disorder in Europe. The EU-AIMS initiative involves a novel collaboration between academic centers, pharmaceutical & high-tech industry, and organizations representing affected individuals and their families. This makes EU-AIMS a ground-breaking project and the world’s first consortium that will work together to develop the infrastructure underpinning new treatments for autism.
EU-AIMS: a boost to autism research
Noldus Information Technology is one of three innovative SMEs involved in EU-AIMS. Animal models play a key role in this project, with focus on social interaction, communication (ultrasonic vocalization), stereotypic and repetitive behavior in the home cage, and cognitive rigidity. Noldus’ expertise and products are used in various project tasks. These include:
- Automation of the social interaction test (with EthoVision XT);
- Recording ultrasonic vocalizations;
- Analysis of stereotypic behavior patterns (with Theme);
- Integrated analysis of EEG and behavior (with DSI hardware/software).
Noldus will also contribute to the clinical studies in EU-AIMS. Hardware and software will be set up in labs in the Netherlands, United Kingdom, Belgium, Sweden, and Poland. Mother-child interaction will be video recorded at various time points and coded with The Observer XT software. Furthermore, eye tracking will be performed. Using these and other technologies, EU-AIMS hopes to develop a new instrument for early detection and screening of autism.
Noldus has announced new tools for behavioral testing of rodent models of autism at the EU-AIMS annual meeting in Paris. You can read the details here.
- Autism Speaks
- Eli Lilly
- Janssen Pharmaceutica
- King's College London
- Central Institute of Mental Health Mannheim
- Radboud University Medical Centre
- Cambridge University
- Max Planck Institute for Experimental Medicine
- And many more
EU-AIMS is funded as part of the Innovative Medicines Initiative, part of the European Union's Horizon 2020 program.