Morris water maze

Another popular test for spatial learning and memory is the Morris water maze. The water maze consists of a pool, with a hidden platform submerged just below the water surface. During the Morris water maze test, the rat or mouse learns to escape from the water by locating a hidden platform with the help of visual cues. Optionally, the platform is removed in a second phase of the experiment, or placed in another quadrant, to investigate the animal’s response to this new situation.

Noldus offers you the perfect tools for this test. First of all, EthoVision XT will track the behavior, activity, and movement of your animals in high detail. Add a water maze and other equipment to create a complete solution.

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Examples of parameters


Latency to reach the platform. Average distance to platform: Gallagher’s proximity. Total distance swum until reaching the platform. Total percentage of time spent in specific quadrant. Mean swimming velocity. Direction of movement relative to the platform (heading).

Components


EthoVision XT Base EthoVision XT Multiple Body Points Module Camera Computer Installation & training Service contract Optional components EthoVision XT Good Laboratory Practice Module Extra services Typical components Water maze Platform Optional components EthoVision XT Trial & Hardware Control Module On-demand platform

Optional components

EthoVision XT Good Laboratory Practice Module
Extra services

Typical components

Water maze
Platform

Optional components

Selected publications


Nishimura, M.; Gu, X.; Swann, J.W. (2011). Seizures in early life suppress hippocampal dendrite growth while impairing spatial learning. Neurobiology of Disease, 44 (2), 205-214. Zheng, Y.; Hamilton E. (2011). The effects of acoustic trauma that can cause tinnitus on spatial performance in rats. Neuroscience, 186, 48-56. Chevere-Torres, I.; Maki, J.M. (2012). Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin. Neurobiology of Disease, 45 (1), 156-164.

Nishimura, M.; Gu, X.; Swann, J.W. (2011). Seizures in early life suppress hippocampal dendrite growth while impairing spatial learning. Neurobiology of Disease, 44 (2), 205-214.
Zheng, Y.; Hamilton E. (2011). The effects of acoustic trauma that can cause tinnitus on spatial performance in rats. Neuroscience, 186, 48-56.
Chevere-Torres, I.; Maki, J.M. (2012). Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin. Neurobiology of Disease, 45 (1), 156-164.

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