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CatWalk XT
Resources
Recent videos
Goal box CatWalk XT
CatWalk XT includes a goal box to motivate your animal to cross the walkway in a consistent manner
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CatWalk XT and TBI mice
The CatWalk XT gait analysis system can be an incredibly useful tool in assessing the subtle motor deficits exhibited by mice post-TBI, making it ideal for detecting deficits that might not be readily observable to researchers. Read tips about how to use CatWalks XT for TBI models in this free white paper.
Getting the perfect runs
Familiarizing your rats with the CatWalk XT system before you start your experiment makes your job a lot easier. So how do you familiarize and motivate your rats? Kristina Ängeby Möller has a lot of experience with pain research and gait analysis in rats, and shares some tips and tricks in this free white paper!
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Parameters in spinal cord injury
CatWalk XT is an invaluable tool to monitor and quantify gait, in this case for spinal cord injured rats. Parameters such as stride length, base-of-support, print area, and intensity are measured objectively and automatically by CatWalk XT.
Coordination measures in SCI
This user report also focuses on spinal cord injury (SCI). The parameters measured by CatWalk, in particular measures for coordination, are used to test the behavioral implications of voluntary locomotor training induced by enriched housing facilities.
References
Here is a selection of recent papers that mention the use of CatWalk XT. If you feel your paper should be on this list, please let us know at marcom@noldus.nl!
- Bombeiro, A. L., Pereira, B. T. N., & de Oliveira, A. L. R. (2018). Granulocyte‐macrophage colony‐stimulating factor improves mouse peripheral nerve regeneration following sciatic nerve crush. European Journal of Neuroscience, 48(5), 2152-2164.
- Crowley, S. T., Kataoka, K., & Itaka, K. (2018). Combined CatWalk Index: an improved method to measure mouse motor function using the automated gait analysis system. BMC research notes, 11(1), 263.
- De Munter, S., Bamps, D., Malheiro, A. R., Kumar Baboota, R., Brites, P., & Baes, M. (2018). Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein‐2 deficiency. Brain Pathology, 28(5), 631-643.
- Liu, Z., Zhang, H., Xia, H., Wang, B., Zhang, R., Zeng, Q., ... & Li, Z. (2019). CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier. Biochemical and biophysical research communications, 512(2), 367-372.
- Morgan, M., Deuis, J. R., Woodruff, T. M., Lewis, R. J., & Vetter, I. (2018). Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced pain. Molecular immunology, 94, 68-74.
- Moritz, M. S., Tepp, W. H., N'te Inzalaco, H., Johnson, E. A., & Pellett, S. (2019). Comparative functional analysis of mice after local injection with botulinum neurotoxin A1, A2, A6, and B1 by catwalk analysis. Toxicon, 167, 20-28.
- Timotius, I. K., Canneva, F., Minakaki, G., Pasluosta, C., Moceri, S., Casadei, N., ... & Eskofier, B. (2018). Dynamic footprints of α-synucleinopathic mice recorded by CatWalk gait analysis. Data in brief, 17, 189-193.
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Recent blog posts
What gait can tell: 3 blogs that will help you understand
The usefulness of gait is well established in research on spinal cord injury, ataxia, and arthritis. But in fact, research on all disorders that influence gait in any way, can benefit from gait and footfall analysis.
Parkinson's disease research - Relevant measures in pre-clinical studies
Parkinson’s disease: the neurodegenerative disorder that affects mobility in a life-changing way. Learn more about relevant measures in pre-clinical studies.